What is Bile Acid Sequestrants?
One of the most effective medications in lowering down high cholesterol level is combining bile Acid sequestrants with statin. We will check what is this drug and how does it work?
BAS (bile acid sequestrants ) bind with cholesterol-containing bile acid in the intestines to be eliminated in the stool. The effect of BAS is to lower cholesterol level down by about 10-20%. Taking small doses of this drug can greatly reduce LDL cholesterol. If combined with statin, BAS can reduce LDL cholesterol by about 40%. Effective as it is with LDL cholesterol, BAS cannot lower down triglycerides.
Anyone can take bile acid sequestrants except for those allergic to this drug or have a medical history of bile obstruction. Patients with phenylketonuria should not take this drug too......Read More >>
What is Cholesterol Absorption Inhibitor?
Ezetimibe (Zetia) is a common cholesterol absorption inhibitor prescribed by doctors. Cholesterol absorption inhibitors are a class of compounds that prevents cholesterol from being absorbed from the small intestines into the circulatory system. Ezetimibe is an effective medication for those people who cannot take statins or those who experience side effects when dose of statins are increased.
Ezetimibe reduces LDL cholesterol by 18-20%. This is achieved by selectively decreasing cholesterol absorption. It can also reduce triglyceride level albeit mildly. While a good substitute for statins, it can also double to triple the effect of statins if the two are taken together. ......Read More >>
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